Sir2 is required for the quiescence-specific condensed three-dimensional chromatin structure of rDNA
Christine E. Cucinotta, Rachel Dell, Kris G. Alavattam, Toshio Tsukiyama
This study identifies a unique condensed 3D chromatin structure of rDNA in quiescent yeast cells and shows that Sir2 is essential for maintaining this structure and proper quiescence transitions.
bioRxiv · Dec 12, 2024 · PreprintMolecular Biology