Molecular BiologyNature CommunicationsPeer-reviewed
Epigenetic lockdown of type I interferon sensing and signalling in human pluripotent cells.
James H. Holt, Rocio Enriquez-Gasca, Rachel P. Wilson…·Helen M. Rowe
This study investigates how the HUSH complex suppresses the type I interferon pathway in human pluripotent cells, revealing its role in preventing self-nucleic acid sensing and maintaining immune evasion.
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