STAT3 and HIF1α cooperatively mediate the transcriptional and physiological responses to hypoxia
Alberto Dinarello, Riccardo Massimiliano Betto, Linda Diamante, Annachiara Tesoriere, Rachele Ghirardo, Chiara Cioccarelli, Giacomo Meneghetti, Margherita Peron, Claudio Laquatra, Natascia Tiso, Graziano Martello, Francesco Argenton
This study shows that STAT3 and HIF1α work together to mediate hypoxia responses by physically interacting and enhancing HIF1α transcriptional activity.
Cell Death Discovery · Jul 5, 2023Peer-reviewedDevelopmental Biology