Polyploid cancer cells reveal signatures of chemotherapy resistance
Michael J. Schmidt, Amin Naghdloo, Rishvanth K. Prabakar, Mohamed Kamal, Radu M. Cadaneanu, Isla P. Garraway, Michael S. Lewis, Ana M. Aparicio, Amado J. Zurita, Paul Gettys Corn, Peter Kühn, Kenneth J. Pienta, Sarah R. Amend, James B Hicks
The paper identifies polyploid cancer cells as markers of chemotherapy resistance and recurrence in prostate cancer, linking them to poorer survival outcomes.
Oncogene · Nov 22, 2024Peer-reviewedCancer Biology