Discovery of three novel neutralizing antibody epitopes on the human astrovirus capsid spike and mechanistic insights into virus neutralization
Sarah Lanning, Nayeli Aguilar-Hernández, Vitor Hugo Balasco Serrão, Tomás López, Sara M. O’Rourke, Adam Lentz, Lena Ricemeyer, Rafaela Espinosa, Susana López, Carlos Federico Arias, Rebecca M. DuBois
This study identifies three novel neutralizing antibody epitopes on the human astrovirus capsid spike using structural biology techniques and shows their role in blocking virus neutralization.
Journal of Virology · Jan 23, 2025Peer-reviewedMicrobiology