Accelerated amyloid neurodegeneration in HIV-1-infected APP-KI Alzheimer's disease mice
Shaurav Bhattarai, Emma G. Foster, Rana Kadry, Yaman Lu, Mohit Kumar, Syed Qasim, Amrita Mitra, Harsh B. Pathak, Larisa Y. Poluektova, Santhi Gorantla, Rodney Lee Mosley, Pravin Yeapuri, Howard Eliot Gendelman
This study shows that HIV-1 infection accelerates amyloid pathology and neurodegeneration in a novel AD mouse model with human microglia-like cells.
bioRxiv · May 19, 2026 · PreprintNeuroscience