Author

Howard Eliot Gendelman

University of Nebraska Medical CenterORCID 0000-0002-7831-0370Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 3

Signature Assays, Organisms & Methods

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Organism:mouse· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Approach:experimental assay· 1 Assay:proteomics· 1

Frequent Co-Authors

Santhi GorantlaiD· 3 shared Larisa Y. PoluektovaiD· 2 shared Amrita MitraiD· 1 shared Asuka Yoshii-Kitahara· 1 shared Dhruba PathakiD· 1 shared Emma G. FosteriD· 1 shared Harsh B. PathakiD· 1 shared Jennifer Irene LuebkeiD· 1 shared

Activity by Year

2017-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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3 shared papersNeuroscience

Santhi GorantlaORCID

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3 papers

Recent·Most cited

NeurosciencebioRxivPreprintMay 19, 2026

Accelerated amyloid neurodegeneration in HIV-1-infected APP-KI Alzheimer's disease mice

Shaurav Bhattarai, Emma G. Foster, Rana Kadry…·Howard Eliot Gendelman

This study shows that HIV-1 infection accelerates amyloid pathology and neurodegeneration in a novel AD mouse model with human microglia-like cells.

DOI 10.64898/2026.05.16.725620

mousespatial transcriptomics

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NeuroscienceBrainPeer-reviewedOct 7, 2020

Alzheimer's disease brain-derived tau-containing extracellular vesicles: Pathobiology and GABAergic neuronal transmission

Zhi Ruan, Dhruba Pathak, Srinidhi Venkatesan Kalavai…·Tsuneya Ikezu

This study investigates how Alzheimer's disease-derived extracellular vesicles propagate tau pathology and affect GABAergic neuronal transmission.

283 citationstop 1%

mouseproteomics

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NeuroscienceDisease Models & MechanismsPeer-reviewedJan 1, 2017

Systemic HIV-1 Infection Produces a Unique Glial Footprint in Humanized Mouse Brains

Weizhe Li, Santhi Gorantla, Howard Eliot Gendelman, Larisa Y. Poluektova

This paper creates a humanized mouse model to study HIV-1's effects on glial cells, finding human-specific transcriptional changes in antiviral responses and myelination.

26 citations

mousebulk RNA-seq

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