Author

Larisa Y. Poluektova

University of Nebraska Medical CenterORCID 0000-0001-7339-8732Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Approach:experimental assay· 1 Assay:spatial transcriptomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Howard Eliot GendelmaniD· 2 shared Santhi GorantlaiD· 2 shared Amrita MitraiD· 1 shared Emma G. FosteriD· 1 shared Harsh B. PathakiD· 1 shared Mohit Kumar· 1 shared Pravin Yeapuri· 1 shared Rana Kadry· 1 shared

Activity by Year

2017-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersNeuroscience

Howard Eliot GendelmanORCID

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2 papers

Recent·Most cited

NeurosciencebioRxivPreprintMay 19, 2026

Accelerated amyloid neurodegeneration in HIV-1-infected APP-KI Alzheimer's disease mice

Shaurav Bhattarai, Emma G. Foster, Rana Kadry…·Howard Eliot Gendelman

This study shows that HIV-1 infection accelerates amyloid pathology and neurodegeneration in a novel AD mouse model with human microglia-like cells.

DOI 10.64898/2026.05.16.725620

mousespatial transcriptomics

𝕏 PostBluesky

NeuroscienceDisease Models & MechanismsPeer-reviewedJan 1, 2017

Systemic HIV-1 Infection Produces a Unique Glial Footprint in Humanized Mouse Brains

Weizhe Li, Santhi Gorantla, Howard Eliot Gendelman, Larisa Y. Poluektova

This paper creates a humanized mouse model to study HIV-1's effects on glial cells, finding human-specific transcriptional changes in antiviral responses and myelination.

26 citations

mousebulk RNA-seq

𝕏 PostBluesky