Social isolation of aged mice drives dramatic release of inflammatory lipoxygenase-derived oxylipins
Mareike Wichmann-Costaganna, Raphaelle Petit, Julia Lindner, Madlen Haase, Vivien Bachmann, Robert Klaus Hofstetter, Markus Werner, Christiane Frahm, Oliver Werz, Patrick Schädel
This study shows social isolation in aged mice increases inflammatory oxylipins in multiple organs but not serum, with exercise failing to reduce these effects.
npj Aging · May 16, 2026Peer-reviewedImmunology