Disentangling the effects of Corticotrophin Releasing Factor and GABA release from the ventral bed nucleus of the stria terminalis on ethanol self-administration in mice
Carol A. Gianessi, Harold L. Haun, Dipanwita Pati, Tori R. Sides, Shannon D’Ambrosio, Willem P. Kelson, Raul Hernandez, Graydon B. Gereau, Kristen M. Boyt, Clyde W. Hodge, Thomas L. Kash
This study investigates the separate roles of CRF and GABA release from BNSTCRF neurons in ethanol self-administration in mice, finding CRF deletion reduces ethanol intake while GABA suppression affects motivation differently in males and females.
Neuropsychopharmacology · Sep 6, 2025Peer-reviewedNeuroscience