Harold L. Haun

Disentangling the effects of Corticotrophin Releasing Factor and GABA release from the ventral bed nucleus of the stria terminalis on ethanol self-administration in mice

This study investigates the separate roles of CRF and GABA release from BNSTCRF neurons in ethanol self-administration in mice, finding CRF deletion reduces ethanol intake while GABA suppression affects motivation differently in males and females.

Septo-hypothalamic regulation of binge-like alcohol consumption by the nociceptin system.

This study identifies a population of nociceptin-expressing neurons in the lateral septum that modulate binge-like alcohol consumption and shows sex-dependent effects of NOP receptor deletion.

Inhibiting CRF Projections from the Central Amygdala to Lateral Hypothalamus and Amygdala Deletion of CRF Alters Binge-Like Ethanol Drinking in a Sex-Dependent Manner

This study shows that inhibiting CRF projections from the central amygdala to the lateral hypothalamus reduces binge-like ethanol drinking in male, but not female, mice.

Retrieval of an ethanol-conditioned taste aversion promotes GABAergic plasticity in the insular cortex

This study shows that retrieving an ethanol-conditioned taste aversion increases GABAergic plasticity in insular cortex-BLA projection neurons, with a male-specific role for parvalbumin-expressing interneurons.

Dynamic regulation of CeA gene expression during acute and protracted abstinence from chronic binge drinking of male and female C57BL/6J mice.

This study examines gene expression changes in the CeA of male and female mice during acute and protracted abstinence from binge drinking, revealing sex-specific differences in gene regulation.

Alcohol dependence modifies brain networks activated during abstinence and reaccess: a c-fos-based analysis in mice

The paper uses c-fos mapping and network analysis to show that alcohol dependence alters brain network activity during abstinence and reaccess in mice, with increased network modularity in high-drinking mice after reaccess.

Chronic Alcohol Consumption Alters Home-Cage Behaviors and Responses to Ethologically Relevant Predator Tasks in Mice

This study examines how chronic alcohol consumption affects behavior in mice during different predator threat tasks, revealing sex-specific changes in stress coping responses.

Activation of the dorsal septum increases alcohol consumption in male C57BL/6J mice.

This study shows that activating the dorsal septum increases binge-like alcohol consumption in male mice, with sex-dependent effects on locomotor activity and sucrose drinking.

Sex-specific regulation of binge drinking and affective behaviors by subcortical serotonin 5HT2c receptor-containing neurons

This study identifies sex-specific roles of serotonin 5HT2c receptor-containing neurons in binge drinking and affective behaviors using rodent models.