Sophia Lee

Sex Differences in BNST Signaling and BNST CRF in Fear Processing: Implications for Unpredictable Threat in Sustained Fear

This study examines sex differences in BNST CRF signaling during phasic and sustained fear in mice, finding sex-specific effects on fear responses and suggesting implications for anxiety treatment.

Septo-hypothalamic regulation of binge-like alcohol consumption by the nociceptin system.

This study identifies a population of nociceptin-expressing neurons in the lateral septum that modulate binge-like alcohol consumption and shows sex-dependent effects of NOP receptor deletion.

Inhibiting CRF Projections from the Central Amygdala to Lateral Hypothalamus and Amygdala Deletion of CRF Alters Binge-Like Ethanol Drinking in a Sex-Dependent Manner

This study shows that inhibiting CRF projections from the central amygdala to the lateral hypothalamus reduces binge-like ethanol drinking in male, but not female, mice.

Impact and role of hypothalamic corticotropin releasing hormone neurons in withdrawal from chronic alcohol consumption in female and male mice.

This study examines how chronic alcohol consumption affects hypothalamic CRH neurons in male and female mice during withdrawal, revealing sex-specific changes in stress responses and neuronal excitability.