Bisdemethoxycurcumin mitigates Alzheimer disease pathology through autophagy-mediated reduction of senescence and amyloid beta
Parul Khajuria, Dilpreet Kour, Kuhu Sharma, Lakhvinder Singh, Razia Banoo, Diksha Manhas, P. Ramajayan, Utpal Nandi, Sandip Bibishan Bharate, Zabeer Ahmed, Ajay Kumar
This study shows that BDMC improves AD pathology by enhancing autophagy, reducing senescence, and lowering amyloid beta in both astrocytes and a mouse model.
bioRxiv · May 19, 2025 · PreprintPharmacology & Toxicology