Positive allosteric modulation of emodepside sensitive Brugia malayi SLO-1F and Onchocerca volvulus SLO-1A potassium channels by GoSlo-SR-5-69
Mark Andrew McHugh, Charity Nya Njeshi, Nathaniel Smith, Sudhanva Srinivas Kashyap, Real Datta, Han Sun, Alan Patrick Robertson, Richard J. Martin
This study identifies GoSlo-SR-5-69 as a positive allosteric modulator that enhances emodepside's potency against Brugia malayi SLO-1 K channels.
PLoS Pathogens · Sep 11, 2025Peer-reviewedPathology