Author

Han Sun

Leibniz-Forschungsinstitut für Molekulare PharmakologieORCID 0009-0003-3825-5797Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Han Sun4 papers · Leibniz-Forschungsinstitut für Molekulare Pharmakologie

Biology Disciplines

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Biophysics· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:drug response / drug discovery· 1 Assay:electrophysiology· 1 Research Focus:host-pathogen & immune response· 1 Approach:mechanistic / dynamical model· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

Alan Patrick RobertsoniD· 1 shared Berke TürkaydiniD· 1 shared Chaimae BenkerdaghiD· 1 shared Charity Nya Njeshi· 1 shared Francesco Luigi GervasioiD· 1 shared Marcus ScheweiD· 1 shared Mark Andrew McHugh· 1 shared Nathaniel Smith· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperPathology

Alan Patrick RobertsonORCID

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2 papers

Recent·Most cited

BiophysicsbioRxivPreprintFeb 14, 2026

Energetic cross-talk of filter gate and lower helices drives polymodal regulation and disease in TREK K2P channels

Berke Türkaydin, Valerio Rizzi, Chaimae Benkerdagh…·Han Sun

This study uses molecular dynamics to analyze TREK-2 channel conformational changes, linking them to disease mechanisms and drug discovery.

DOI 10.64898/2026.02.13.705734

electrophysiologymechanistic / dynamical model

𝕏 PostBluesky

PathologyPLoS PathogensPeer-reviewedSep 11, 2025

Positive allosteric modulation of emodepside sensitive Brugia malayi SLO-1F and Onchocerca volvulus SLO-1A potassium channels by GoSlo-SR-5-69

Mark Andrew McHugh, Charity Nya Njeshi, Nathaniel Smith…·Richard J. Martin

This study identifies GoSlo-SR-5-69 as a positive allosteric modulator that enhances emodepside's potency against Brugia malayi SLO-1 K channels.

2 citations

experimental assayhost-pathogen & immune response

𝕏 PostBluesky