Author

Rebecca A. Splain

Howard Hughes Medical Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:protein folding & dynamics· 1 Assay:protein sequence· 1

Frequent Co-Authors

Alexander A. VinogradoviD· 1 shared Dinh Thanh NguyeniD· 1 shared Douglas A. MitchelliD· 1 shared Hiroaki SugaiD· 1 shared Josseline S. Ramos‐FigueroaiD· 1 shared Mayuresh G. GadgiliD· 1 shared Wilfred A. van der DonkiD· 1 shared Yuki GotoiD· 1 shared

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2025-2025 · peak 1/yr

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1 shared paperBiochemistry

Alexander A. VinogradovORCID

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1 paper

Recent·Most cited

Aminoacyl-tRNA specificity of a ligase catalyzing non-ribosomal peptide extension

Dinh Thanh Nguyen, Josseline S. Ramos‐Figueroa, Alexander A. Vinogradov, Yuki Goto, Mayuresh G. Gadgil, Rebecca A. Splain, Hiroaki Suga, Wilfred A. van der Donk, Douglas A. Mitchell

This study investigates the substrate specificity of the PEARL BhaBCAla, showing it can use non-cognate amino acids and tRNAs for peptide extension, with efficiency depending on both amino acid and tRNA features.

Journal of the American Chemical Society · Oct 9, 2025Peer-reviewedBiochemistry