MicrobiologybioRxivPreprint
SARS-CoV-2 Spike H655Y drives protease preference but does not dictate cellular tropism
Diego M. Cantoni, Wilhelm Furnon, Sarah Little…·Joe Grove
This study shows that the SARS-CoV-2 Spike H655Y mutation changes protease preference but does not determine cellular tropism, with RBD interactions being more critical for upper airway adaptation.
DOI 10.64898/2026.07.05.736580