Author

Sarah Little

MRC University of Glasgow Centre for Virus Research

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

Arvind H. PateliD· 1 shared Brian Willet· 1 shared Bridget Larman· 1 shared Diego M. CantoniiD· 1 shared Joe GroveiD· 1 shared Massimo PalmariniiD· 1 shared Reehana Damasceno· 1 shared Vanessa M. CowtoniD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 36 mutual co-author links

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1 shared paperMicrobiology

Arvind H. PatelORCID

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1 paper

Recent·Most cited

SARS-CoV-2 Spike H655Y drives protease preference but does not dictate cellular tropism

Diego M. Cantoni, Wilhelm Furnon, Sarah Little, Vanessa M. Cowton, Bridget Larman, Reehana Damasceno, Brian Willet, Arvind H. Patel, Massimo Palmarini, Joe Grove

This study shows that the SARS-CoV-2 Spike H655Y mutation changes protease preference but does not determine cellular tropism, with RBD interactions being more critical for upper airway adaptation.

bioRxiv · Jul 6, 2026 · PreprintMicrobiology