Author

Renata C. Fleith

The Pirbright Institute

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Biology Disciplines

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Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Daniel Santos MansuriD· 1 shared Edward EmmottiD· 1 shared Harriet V MearsiD· 1 shared Taíssa Ricciardi-JorgeiD· 1 shared Trevor R. SweeneyiD· 1 shared Xin Yun Leong· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 15 mutual co-author links

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1 shared paperImmunology

Daniel Santos MansurORCID

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1 paper

Recent·Most cited

IFIT3 controls IFIT1 accumulation and specificity preventing self mRNA targeting during the innate immune response.

Renata C. Fleith, Xin Yun Leong, Taíssa Ricciardi-Jorge, Harriet V Mears, Edward Emmott, Daniel Santos Mansur, Trevor R. Sweeney

The paper shows IFIT3 regulates IFIT1 stability and activity, preventing self mRNA targeting while maintaining antiviral function during the innate immune response.

bioRxiv · Nov 17, 2025 · PreprintImmunology