ImmunologybioRxivPreprint
IFIT3 controls IFIT1 accumulation and specificity preventing self mRNA targeting during the innate immune response.
Renata C. Fleith, Xin Yun Leong, Taíssa Ricciardi-Jorge…·Trevor R. Sweeney
The paper shows IFIT3 regulates IFIT1 stability and activity, preventing self mRNA targeting while maintaining antiviral function during the innate immune response.
DOI 10.1101/2025.11.17.688928