Author

Reuben Sindayiheba

Rwanda Biomedical Center

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genetic & Genomic Medicine· 3 Genomics· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 4 Assay:whole-genome sequencing· 4 Research Focus:variant calling· 3 Research Focus:phylogenetics / evolution· 2 Research Focus:database / resource· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Léon MutesaiD· 3 shared Misbah GasheguiD· 3 shared Yvan ButeraiD· 3 shared Aine Niamh O’TooleiD· 2 shared Alice Kabanda· 2 shared Espérance UmumararunguiD· 2 shared Guy BaeleiD· 2 shared Jean Paul RwabihamaiD· 2 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersGenetic & Genomic Medicine

Léon MutesaORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Persistent circulation of Rift Valley fever virus lineage C in Rwanda, 2022-2025

Jean Claude Udahemuka, Hayley Cassidy, Leonard Schuele, Evodie Uwibambe, Methode Ngabo Gasana, Leandre Murhula Masirika, Reuben Sindayiheba, Saria Otani, Misbah Gashegu, Jean‐Claude Twizere, Frank M. Aarestrup, Fabrice Ndayisenga, Bas B. Oude Munnink, Marion Koopmans, Pacifique Ndishimye

This study shows Rift Valley fever virus lineage C circulates persistently in Rwanda through local transmission, not repeated introductions, based on whole-genome sequencing of livestock samples from 2022-2025.

One Health · Aug 2, 2026Peer-reviewedGenomics

Genomic characterization uncovers transmission dynamics of Marburg Virus in Rwanda following a single zoonotic spillover event

Yvan Butera, Léon Mutesa, Edyth Parker, Raissa Muvunyi, Espérance Umumararungu, Alisen Ayitewala, Jean Pierre Musabyimana, Alhaji S. Olono, Placide Sesonga, Olusola Akinola Ogunsanya, Emmanuel Kabalisa, Oluwatobi Adedokun, Nelson Gahima, Laetitia Irankunda, Chantal Mutezemariya, , Claude Mambo Muvunyi

The paper uses genomic analysis to show the Rwanda MVD outbreak originated from a single zoonotic event with limited human-to-human transmission.

medRxiv · Nov 1, 2024 · PreprintGenetic & Genomic Medicine

SARS-CoV-2 genomic surveillance in Rwanda: Introductions and local transmission of the B.1.617.2 (Delta) variant of concern

Yvan Butera, Samuel Leandro Hong, Muhammed Semakula, Nena Bollen, Verity Hill, Aine Niamh O’Toole, Barney I. Potter, Dieudonné Mutangana, Reuben Sindayiheba, Robert Rutayisire, Maria Artesi, Vincent Bours, Nadine Rujeni, Simon Dellicour, Keith Durkin, , Guy Baele

This study reports genomic surveillance in Rwanda from June to September 2021, showing the rapid spread and dominance of the Delta variant over other lineages, with implications for cross-border transmission.

medRxiv · May 31, 2022 · PreprintGenetic & Genomic Medicine

Genomic Sequencing of SARS-COV-2 in Rwanda: evolution and regional dynamics

Yvan Butera, Enatha Mukantwari, Maria Artesi, Jeanne d’Arc Umuringa, Aine Niamh O’Toole, Verity Hill, Stefan Rooke, Samuel Leandro Hong, Simon Dellicour, Onesphore Majyambere, Sébastien Bontems, Bouchra Boujemla, Josh Quick, Paola Cristina Resende, Nick Loman, , Nadine Rujeni

This study analyzes SARS-CoV-2 genomic sequences from Rwanda to track variant evolution and regional spread, identifying emerging sub-lineages and VOCs introduced through travel.

Nature Communications · Sep 29, 2021Peer-reviewedGenetic & Genomic Medicine