A Highly Protective Clade 1 and 2 Cross-Reactive Pandemic Influenza Virus Vaccine Based on a 4th Generation Fully Deleted Adenoviral Vector of a Rare Serotype
Yan Qi, Richard Bowen, Airn E. Hartwig, Janae Wheeler Cull, Jessica Kelly, Xenia Klimenova, Uwe D. Staerz
The paper develops a cross-reactive influenza vaccine using a rare Ad6 vector that protects against clade 1 and 2 H5 viruses in mice and ferrets.
bioRxiv · Apr 30, 2025 · PreprintImmunology