An H4K20me3-CTCF switch at stable TAD boundaries enforces reversible cell state transitions
Kaiser Atai, Mithun Mitra, Eliana Bohn, Richard Hu, Adriana Z. Corvalan, David Jelínek, Laurent Voisin, Aaron Ambrus, Kirthana Sarathy, William Mason Sparks, Kenya Bonitto, Alex Dunkwu, Hilary A. Coller
The paper identifies an H4K20me3-CTCF switch at TAD boundaries that regulates reversible cell state transitions between proliferation and quiescence.
bioRxiv · Sep 30, 2026 · PreprintCell Biology