Christiano Tanese de Souza

The paper identifies PI3K-gamma signaling as a key pathway in surgery-induced MDSCs that suppresses NK cells and promotes metastases, showing that targeting this pathway can reduce postoperative metastases.

This study identifies LAG3 as a marker of dysfunctional NK cells that are activated but hyporesponsive in various inflammatory conditions.

This study examines how cancer surgery affects T and B cell responses to a model antigen, showing reduced cytokine-producing CD8+ T cells and antibody-secreting B cells post-surgery.