Combining Machine Learning and Multiplexed, In Situ Profiling to Engineer Cell Type and Behavioral Specificity
Michael J. Leone, Robert van de Weerd, Ashley R. Brown, Myung‐chul Noh, BaDoi N. Phan, Andrew Z. Wang, Kelly A. Corrigan, Deepika Yeramosu, Heather H. Sestili, Cynthia Mary Arokiaraj, Bettega Costa Lopes, Vijay Kiran Cherupally, Daryl Pinion Fields, Sudhagar Babu, Chaitanya Srinivasan, , Andreas R. Pfenning
The paper develops a platform combining machine learning and multiplexed in situ screening to identify enhancers with cell-type and behavioral specificity for neural circuit engineering.
bioRxiv · Jun 20, 2025 · PreprintNeuroscience