Protein accumulation upstream of Cdk1 activation regulates the competence and the timing of meiosis resumption
Mariam Gachechiladze, Sarah B. Eivers, Robert Poulhe, Matthew Sonnett, Leonid Peshkin, Catherine Jessus, Enrico Maria Daldello
The paper shows that protein accumulation upstream of Cdk1 activation regulates meiosis resumption timing and competence in oocytes through stepwise acquisition of regulatory mechanisms.
bioRxiv · Jun 26, 2026 · PreprintDevelopmental Biology