Extracellular matrix dependent regulation of Septin 7 in focal adhesions promotes mechanosensing and response in fibroblasts.
Wesley Sturgess, Swathi Packirisamy, Rodina Geneidy, Pontus Nordenfelt, Vinay Swaminathan
This study shows Septin-7 is an FA protein regulated by ECM and integrin activation, which differentially regulates FA subpopulations to promote mechanosensing and ECM remodeling in fibroblasts.
iScience · Nov 9, 2024Peer-reviewedCell Biology