Author

Swathi Packirisamy

Lund UniversityORCID 0000-0001-6764-1302Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:imaging· 1 Approach:microscopy & imaging analysis· 1

Frequent Co-Authors

Pontus NordenfeltiD· 2 shared Vinay SwaminathaniD· 2 shared Oscar AndréiD· 1 shared Rodina Geneidy· 1 shared Wesley SturgessiD· 1 shared Zhimeng FaniD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 11 mutual co-author links

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2 shared papersCell Biology

Pontus NordenfeltORCID

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2 papers

Recent·Most cited

Cell BiologyAdvanced SciencePeer-reviewedMar 31, 2026

ECM-stiffness mediated persistent fibroblast activation requires integrin and formin dependent chromatin remodeling

Swathi Packirisamy, Oscar André, Zhimeng Fan…·Vinay Swaminathan

This study shows that prolonged exposure to stiff ECM activates fibroblasts through integrin and formin pathways, leading to persistent activation and fibrosis, with chromatin remodeling playing a key role.

5 citationstop 1%

humanexperimental assay

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Cell BiologyiSciencePeer-reviewedNov 9, 2024

Extracellular matrix dependent regulation of Septin 7 in focal adhesions promotes mechanosensing and response in fibroblasts.

Wesley Sturgess, Swathi Packirisamy, Rodina Geneidy…·Vinay Swaminathan

This study shows Septin-7 is an FA protein regulated by ECM and integrin activation, which differentially regulates FA subpopulations to promote mechanosensing and ECM remodeling in fibroblasts.

9 citations

imagingmicroscopy & imaging analysis

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