Author

Rodrigo Benedetti Gassen

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Immunology· 1

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Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Assay:flow cytometry· 1 Research Focus:host-pathogen & immune response· 1 Assay:imaging· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Ana Paula Duarte de Souza· 1 shared Andre Bafica· 1 shared Cristina Bonorino· 1 shared Daniel A. G. Bueno Mendes· 1 shared Deise Nascimento de Freitas· 1 shared Fabio Maito· 1 shared Luiz Carlos Rodrigues· 1 shared Thiago Jesus Borges· 1 shared

Activity by Year

2017-2017 · peak 1/yr

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9 top collaborators · 36 mutual co-author links

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1 shared paperImmunology

Ana Paula Duarte de Souza

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1 paper

Recent·Most cited

ImmunologybioRxivPreprintNov 8, 2017

RSV Downregulates IL-21/IL-21R On TFH Cells Via PD-L1 Induction In APCs Impairing Protective Humoral Responses

Rodrigo Benedetti Gassen, Tiago Fazolo, Deise Nascimento de Freitas…·Cristina Bonorino

This study shows RSV impairs TFH cell function by inducing PD-L1 on APCs, reducing IL-21 and its receptor, which weakens humoral immunity, but IL-21 treatment can restore immune responses and protect against RSV infection.

DOI 10.1101/203133

mouseimaging