Implantable Living Materials Autonomously Deliver Therapeutics from Contained Engineered Bacteria
Tetsuhiro Harimoto, Fernando Quevedo, Janis Zillig, Sanjay Schreiber, Yi Xi Wu, Christine Heera Ahn, Tania To, Rohan Thakur, Alexander M. Tatara, Shawn J. Kang, Zheqi Chen, Shanda L. Lightbown, David A. Weitz, David J. Mooney
This paper presents an implantable material platform that contains engineered bacteria to autonomously deliver therapeutics in a mouse model of prosthetic joint infection.
bioRxiv · Oct 9, 2025 · PreprintBioengineering