Comprehensive Mapping of the Virus and Host Factors that Guide the Paths of HIV-1 Escape from a Therapeutic
Aaron Nicholas Gillman, Cassian M Birler, Rohith Rao Vujjini, Mohammad Fili, Samuel A McCarthy-Potter, Wilson Chen, Madeline M Broghammer, Guiping Hu, Margaret J. Gartland, Manyu Prakash, Annika Helverson, Grant Brown, Hillel Haim
The paper identifies HIV-1 mutations that confer resistance to temsavir and shows how mutation probability and host immunity influence their emergence in vivo.
Cell Reports · Jun 19, 2026Peer-reviewedMicrobiology