Author

Roma Karna

The Ohio State University Wexner Medical Center

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

Ali F. UsmaniiD· 1 shared Connor P Harper· 1 shared Federica Calore· 1 shared Fernanda Costas Casal de FariaiD· 1 shared Jay K. MandulaiD· 1 shared Jing Wang· 1 shared Patricia Sarchet· 1 shared Premanshu K. Singh· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Ali F. UsmaniORCID

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1 paper

Recent·Most cited

Extracellular vesicle-mediated suppression of macrophage STING signaling promotes immune dysfunction in dedifferentiated liposarcoma

Qi Zhang, Jay K. Mandula, Patricia Sarchet, Priya Dhawale, Fernanda Costas Casal de Faria, Timothy Zhang, Sydney Rentsch, Premanshu K. Singh, Ali F. Usmani, Roma Karna, Connor P Harper, Valerie Patrice Grignol, Jing Wang, Yong Zhang, Zihai Li, , Federica Calore

This study shows that extracellular vesicles from dedifferentiated liposarcoma suppress macrophage STING signaling, leading to immune dysfunction and poor response to immunotherapy.

bioRxiv · Aug 10, 2026 · PreprintCancer Biology