A photo-switchable yeast isocitrate dehydrogenase to control metabolic flux through the citric acid cycle
Haoqi Chen, Lianne M. Mulder, Hein J. Wijma, Ronja Wabeke, José Losa, Mattia Rovetta, Tijn C. de Leeuw, Andreas Milias‐Argeitis, Matthias Heinemann
This paper develops a photo-switchable isocitrate dehydrogenase in yeast to dynamically control citric acid cycle flux using optogenetics.
bioRxiv · May 25, 2021 · PreprintSynthetic Biology