Exocyst Inactivation in Urothelial Cells Disrupts Autophagy and Activates non-canonical NF-kB
Michael A. Ortega, Ross Villiger, Malia H. Harrison-Chau, Suzanna Lieu, Kadee‐Kalia Tamashiro, Amanda J. Lee, B. Fujimoto, Geetika Y. Patwardhan, Joshua K. Kepler, Ben Fogelgren
This study shows that Exoc5 ablation disrupts autophagy in urothelial cells, activates non-canonical NF-κB signaling, and leads to ureter obstruction.
Disease Models & Mechanisms · Aug 25, 2022Peer-reviewedDevelopmental Biology