An Integrative Framework For Detecting Structural Variations In Cancer Genomes
Jesse R. Dixon, Jie Xu, Vishnu Dileep, Ye Zhan, Fan Song, Victoria T. Le, Galip Gürkan Yardımcı, Abhijit Chakraborty, Darrin V. Bann, Yanli Wang, Royden A. Clark, Lijun Zhang, Hongbo Yang, Tingting Liu, Sriranga Iyyanki, , Feng Yue
This paper presents an integrative framework to detect structural variants in cancer genomes using multiple methods and finds that non-coding structural variation significantly impacts genome function in cancer cells.
Nature Genetics · Sep 4, 2018Peer-reviewedGenomics