Author

Rui Xu

Beijing University of Posts and Telecommunications

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Biology Disciplines

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Bioinformatics· 1 Cancer Biology· 1 Immunology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:benchmarking· 2 Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Research Focus:dimensionality reduction· 1

Frequent Co-Authors

Aaron N. HataiD· 1 shared Alison Caron· 1 shared Andrew Burns· 1 shared Anna E. MaciagiD· 1 shared Azar AlizadehiD· 1 shared Bin Wang· 1 shared Bo ZhangiD· 1 shared Brian Davis· 1 shared

Activity by Year

2024-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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1 shared paperCancer Biology

Aaron N. HataORCID

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Author profile →

4 papers

Recent·Most cited

Dual inhibition of GTP-bound (ON) and GDP-bound (OFF) KRASG12C suppresses PI3Kα and leads to potent tumor inhibition

Katherine Parker, Samar Ghorbanpoor, Wafa Malik, Lauren Highfield, Jamie Wang, Emily Hensley, Grace Kelley, Sarah Clark, Michela Ranieri, Soumyadip Sahu, Cathy Zhang, Magdalena A. Ploszaj, Daniel Andrussier, Hsin‐Yi Huang, Ting Chen, , Aaron N. Hata

This study shows that a dual inhibitor of KRASG12C in both ON and OFF states more effectively suppresses tumor growth than an OFF-specific inhibitor by reducing PI3K-AKT activation.

bioRxiv · Apr 30, 2026 · PreprintCancer Biology

Integration of Multiomic and Multi-phenotypic Data Identifies Biological Pathways Associated with Physical Fitness

Azar Alizadeh, John F. Graf, Matthew J. Misner, Andrew Burns, Fiona Ginty, Kevin J. O’Donovan, J. Kenneth Wickiser, N Barringer, Gregory M Freisinger, Neil Hermansen, J. Elizabeth McDonough, Brian Davis, Evelina Loghin, Christine Surrette, Peter Tu, , Luca Marinelli

This paper introduces PhenoMol, a framework that integrates multiomic and multi-phenotypic data to identify biological pathways linked to physical fitness, outperforming traditional regression models.

Communications Biology · Feb 17, 2026Peer-reviewedBioinformatics

Distinct Bomanins at the Drosophila 55C locus function in resistance and resilience to infections

Yanyan Lou, Bo Zhang, Zhiyuan Zhang, Yingyi Pan, Jianwen Yang, Lu Li, Jianqiong Huang, Zihang Yuan, Samuel Liégeois, Philippe Bulet, Rui Xu, Li Zi, Dominique Ferrandon

The paper investigates the roles of distinct Bomanin peptides from the 55C locus in Drosophila resistance and resilience to infections, finding overlapping and specific functions against different pathogens.

EMBO Reports · Jan 9, 2026Peer-reviewedImmunology

Functional fingerprinting for the developing brain using deep metric learning: an ABCD study

Rui Xu, Shuwan Zhao, Qianhui Jin, Zeyao Wang, Kun Zhao, Suyu Zhong, Jiaying Zhang, Yong Liu, Ting Qi, Yongbin Wei

This study introduces a deep learning framework for brain fingerprinting using fMRI data from adolescents, achieving high individual identification accuracy and linking fingerprints to cognitive and genetic factors.

bioRxiv · Dec 13, 2024 · PreprintNeuroscience