Ting Chen

This study shows that a dual inhibitor of KRASG12C in both ON and OFF states more effectively suppresses tumor growth than an OFF-specific inhibitor by reducing PI3K-AKT activation.

This paper introduces DD-CIPs, bivalent molecules that induce DNA damage response and apoptosis in cancer cells, showing efficacy against PARPi-resistant cancers.

The paper develops a mouse model of retinal artery occlusion and uses transcriptomics to identify gene expression changes associated with ischemia and reperfusion injury.

The paper introduces FAXP, a method combining hydrogel expansion and mass spectrometry for high-resolution proteomics of FFPE tissues, showing improved resolution and efficiency over existing methods.

This study uses ctDNA analysis to identify genetic mutations and monitor residual disease in NK/T lymphoma patients, finding KMT2D mutations correlate with poor prognosis and treatment response.