The impact of rare protein coding genetic variation on adult cognitive function
Chia‐Yen Chen, Ruoyu Tian, Tian Ge, Max Lam, Gabriela Sánchez-Andrade, Tarjinder Singh, Lea Urpa, Jimmy Z. Liu, Mark Sanderson, Christine Rowley, Holly Ironfield, Terry Fang, Biogen Biobank Team, The SUPER-Finland study, Aija Kyttälä, , Heiko Runz
This study identifies eight genes associated with adult cognitive function through rare coding variants and shows how KDM5B dosage affects cognitive traits in mice and humans.
Nature Genetics · May 25, 2023Peer-reviewedGenetic & Genomic Medicine