(p)ppGpp and DksA play crucial role in reducing the efficacy of b-lactam antibiotics by modulating bacterial membrane permeability
Meenal Chawla, Jyoti Verma, Shashi Kumari, Tushar Matta, Tarosi Senapati, Prabhakar Babele, Yashwant Kumar, Rupak K. Bhadra, Bhabatosh Das
This study shows that (p)ppGpp and DksA reduce the effectiveness of beta-lactam antibiotics by altering bacterial membrane permeability and peptidoglycan biosynthesis in Vibrio cholerae.
Microbiology Spectrum · Feb 24, 2025Peer-reviewedMicrobiology