Bhabatosh Das

Target-Specific Discovery of BMM_1567 Restores Aminoglycoside Activity Against Multidrug-Resistant Gram-Negative ESKAPE Pathogens

This paper identifies BMM_1567, a peptide that enhances aminoglycoside activity against multidrug-resistant Gram-negative bacteria by inhibiting resistance enzymes.

Diabetes mellitus and tuberculosis comorbidity induce unique microbial gut dysbiosis and associated metabolome.

This study investigates gut microbiome and metabolome changes in diabetic mice co-infected with tuberculosis, identifying dysbiosis and metabolic alterations associated with comorbidity.

(p)ppGpp and DksA play crucial role in reducing the efficacy of b-lactam antibiotics by modulating bacterial membrane permeability

This study shows that (p)ppGpp and DksA reduce the effectiveness of beta-lactam antibiotics by altering bacterial membrane permeability and peptidoglycan biosynthesis in Vibrio cholerae.

miRNA synergism impaired metabolic programming of oral cancer cells by selectively enhancing target gene specificity

This study shows that miRNA mimic pairs synergistically reduce target gene expression in oral cancer cells, impairing metabolism and reducing proliferation, but not in normal cells.