eIF2B extends lifespan through inhibition of the integrated stress response
Maxime J. Derisbourg, Laura E. Wester, Ruth Baddi, Martin Sebastian Denzel
This study identifies eIF2B's role in extending lifespan by inhibiting the integrated stress response in C. elegans, improving protein homeostasis without altering overall protein synthesis.
Nature Communications · Mar 15, 2021Peer-reviewedGenetics