Δ9-tetrahydrocannabinol negatively regulates neurite outgrowth and Akt signaling in hiPSC-derived cortical neurons.
Carole Shum, Lucia Dutan Polit, Emily Annuario, Katherine M. Warre-Cornish, Samuel E. Taylor, Ruth D. Taylor, Laura C. Andreae, Noel J. Buckley, Jack Price, Sagnik Bhattacharyya, Deepak P. Srivastava
This study shows that Δ9-THC inhibits neurite outgrowth and Akt signaling in hiPSC-derived cortical neurons via CB1R activation.
bioRxiv · Dec 20, 2018 · PreprintNeuroscience