Laura C. Andreae

This study identifies molecular layer heterotopias and age-dependent cortical expansion in Chd8 haploinsufficient mice, linking them to neuronal migration defects and autism-related brain overgrowth.

This study shows that KDM5B deficiency in mice leads to autism-like behaviors and increased brain size, which can be mitigated by NMDAR antagonists.

This study shows NMDA receptor activation is critical for early synapse formation and dendritic maturation during development.

The paper shows that functional connectivity gradients in resting state networks are present in the human fetal brain from 25 weeks gestation, with spatial consistency increasing in primary sensory and motor networks.

This study examines synaptic imbalances and homeostatic plasticity disruption in ASD-associated Chd8 haploinsufficient mice, revealing altered excitatory and inhibitory transmission in cortical circuits.

This study optimizes and validates a hydrogel-based brain tissue clearing protocol, showing uniform expansion across anatomical regions and spatial scales.

This study uses diffusion tensor MRI and CLARITY to show structural brain changes in Nrxn2 knockout mice, revealing altered connectivity in socially relevant regions.

This study shows that Δ9-THC inhibits neurite outgrowth and Akt signaling in hiPSC-derived cortical neurons via CB1R activation.