Phosphoinositide-focused CRISPR screen identifies novel genetic vulnerabilities in PDAC and AML cells
Daniel K.C. Lee, Ryan Loke, Jonathan Tak-Sum Chow, Martino Gabra, Leonardo Salmena
The paper uses a PI-focused CRISPR screen to identify essential genes and regulators in PDAC and AML cells, revealing novel therapeutic targets and demonstrating the efficiency of focused libraries.
bioRxiv · Sep 9, 2024 · PreprintCancer Biology