Author

Daniel K.C. Lee

University of Toronto

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Approach:genetic perturbation / CRISPR· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Assay:CRISPR screen· 1

Frequent Co-Authors

Jonathan Tak-Sum ChowiD· 2 shared Leonardo SalmenaiD· 2 shared Martino GabraiD· 2 shared Ayeisha DesjardinsiD· 1 shared Byeong Yeop Lee· 1 shared Iulia A Grigore· 1 shared Linda LeeiD· 1 shared Norman J. Fu· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersCancer Biology

Jonathan Tak-Sum ChowORCID

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2 papers

Recent·Most cited

A microRNA CRISPR screen reveals miR-483-3p as an apoptotic regulator in prostate cancer

Jonathan Tak-Sum Chow, Ayeisha Desjardins, Daniel K.C. Lee, Iulia A Grigore, Linda Lee, Norman J. Fu, Stephanie Chau, Byeong Yeop Lee, Martino Gabra, Leonardo Salmena

The paper uses a CRISPR-based screen to identify miR-483-3p as a key apoptotic regulator in prostate cancer, showing its role in cell survival and potential as a therapeutic target.

Cell Death and Disease · Oct 24, 2025Peer-reviewedCancer Biology

Phosphoinositide-focused CRISPR screen identifies novel genetic vulnerabilities in PDAC and AML cells

Daniel K.C. Lee, Ryan Loke, Jonathan Tak-Sum Chow, Martino Gabra, Leonardo Salmena

The paper uses a PI-focused CRISPR screen to identify essential genes and regulators in PDAC and AML cells, revealing novel therapeutic targets and demonstrating the efficiency of focused libraries.

bioRxiv · Sep 9, 2024 · PreprintCancer Biology