Author

Martino Gabra

University of TorontoORCID 0000-0002-5015-4409Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:differential expression· 3 Research Focus:gene regulatory network inference· 3 Organism:human· 3 Research Focus:cell type annotation· 2 Approach:genetic perturbation / CRISPR· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Assay:CRISPR screen· 1

Frequent Co-Authors

Daniel K.C. Lee· 2 shared Jonathan Tak-Sum ChowiD· 2 shared Leonardo SalmenaiD· 2 shared Albi CelajiD· 1 shared Andrew JungiD· 1 shared Ayeisha DesjardinsiD· 1 shared Bhargav KanuparthiiD· 1 shared Brandon VaziD· 1 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersCancer Biology

Daniel K.C. Lee

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

A microRNA CRISPR screen reveals miR-483-3p as an apoptotic regulator in prostate cancer

Jonathan Tak-Sum Chow, Ayeisha Desjardins, Daniel K.C. Lee, Iulia A Grigore, Linda Lee, Norman J. Fu, Stephanie Chau, Byeong Yeop Lee, Martino Gabra, Leonardo Salmena

The paper uses a CRISPR-based screen to identify miR-483-3p as a key apoptotic regulator in prostate cancer, showing its role in cell survival and potential as a therapeutic target.

Cell Death and Disease · Oct 24, 2025Peer-reviewedCancer Biology

Sequence based prediction of cell type specific microRNA binding and mRNA degradation for therapeutic discovery

Bhargav Kanuparthi, Sara E. Pour, Scott D. Findlay, Omar Wagih, Jahir M. Gutierrez, Rory Gao, Jeff A. Wintersinger, Jiun-Nong Lin, Martino Gabra, Emma Bohn, Tammy Lau, Chris Cole, Andrew Jung, Albi Celaj, Fraser Soares, , Brendan J. Frey

This paper introduces REPRESS, a deep learning model that predicts cell-type-specific microRNA binding and mRNA degradation from RNA sequences, outperforming existing methods in multiple tasks.

bioRxiv · May 15, 2025 · PreprintGenomics

Phosphoinositide-focused CRISPR screen identifies novel genetic vulnerabilities in PDAC and AML cells

Daniel K.C. Lee, Ryan Loke, Jonathan Tak-Sum Chow, Martino Gabra, Leonardo Salmena

The paper uses a PI-focused CRISPR screen to identify essential genes and regulators in PDAC and AML cells, revealing novel therapeutic targets and demonstrating the efficiency of focused libraries.

bioRxiv · Sep 9, 2024 · PreprintCancer Biology