Author

Ryan M. Mendel

Children's Hospital of Philadelphia

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Cell Biology· 1

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Organism:C. elegans· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1

Frequent Co-Authors

Alex Lu· 1 shared Marni J. FalkiD· 1 shared Sofie Matsuno· 1 shared Suraiya HarooniD· 1 shared

Activity by Year

2024-2024 · peak 1/yr

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4 top collaborators · 6 mutual co-author links

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1 shared paperCell Biology

Alex Lu

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1 paper

Recent·Most cited

Mitophagy modulation rescues single large-scale mitochondrial DNA deletion (SLSMD) disease symptoms in the C. elegans uaDf5 animal model.

Ryan M. Mendel, Sofie Matsuno, Alex Lu, Marni J. Falk, Suraiya Haroon

This study identifies therapeutic candidates for SLSMD diseases by screening mitophagy modulators in a C. elegans model, showing that Celastrol reduces mitochondrial stress and improves health outcomes.

bioRxiv · Oct 27, 2024 · PreprintCell Biology