Mutability Patterns Across the Spike Glycoprotein Reveal the Diverging and Lineage-specific Evolutionary Space of SARS-CoV-2.
Roberth Anthony Rojas Chávez, Mohammad Fili, Changze Han, Syed Ashiqur Rahman, Isaiah G. L. Bicar, S Gregory, Annika Helverson, Guiping Hu, Benjamin W. Darbro, Jishnu Das, Grant Brown, Hillel Haim
The paper identifies lineage-specific mutability patterns in SARS-CoV-2 spike protein to predict future mutations and guide vaccine/therapeutic design.
PLoS Computational Biology · Jun 10, 2024Peer-reviewedBioinformatics