A liquid-to-solid phase transition of biomolecular condensates drives in vivo formation of yeast amyloids and prions
M. K. Alieva, S. B. Nikishina, I. I. Kireev, S. A. Golyshev, P. A. Tyurin-Kuzmin, L. V. Ivanova, A. I. Alexandrov, V. V. Kushnirov, A. A. Dergalev
The paper investigates how liquid-to-solid phase transitions of prion proteins in yeast lead to amyloid formation and prion conversion, showing differences from cross-seeding mechanisms.
bioRxiv · Nov 17, 2023 · PreprintBiochemistry