Use of steric blocking antisense oligonucleotides for the targeted inhibition of junction containing precursor microRNAs
S. Ma, S. A. Howden, S. C. Keane
This study demonstrates that steric blocking antisense oligonucleotides can inhibit pre-miRNA processing by targeting structural junctions, validating their use in modulating miRNA production.
bioRxiv · Apr 8, 2024 · PreprintBiochemistry